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Phenylpropaniods are organic compounds characterized by having an aromatic ring and a three-carbon propene tail. Polyketides are compounds characterized by having two or more carbonyl functional groups connected with a single carbon atom.
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Tacrolimus is a macrolide immunosuppressant (FK506) used in research to inhibit calcineurin-dependent T-cell activation. It binds FK506-binding protein to form a complex that inhibits calcineurin phosphatase, reducing IL-2 transcription and downstream immune responses. Supplied as a high-purity analytical standard for research and analytical applications.
Inhibits calcineurin-dependent T-cell activation.
Binds FK506-binding proteins to form an inhibitory complex.
High purity (>98%) suitable for analytical work.
Molecular weight 804.02, formula C44H69NO12.
Useful for immunology and signal transduction studies.
Provided in small research quantities appropriate for assays.
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MW 261.27 g/mol. Derivatisation reagent. Fluorescent label for amine modification and protein conjugation. Also used for labeling synthetic peptides for high-throughput detection.
A CYP450 substrate; undergoes O-deethylation by various CYP isoforms; has been used in the functional characterization of CYPs in cats, rats, and isolated human cornea
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Also available in 5 mg 10 mg 25 mg 50 mg 200 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Carmustine (bis-chloroethylnitrosourea) is a cell-cycle phase nonspecific alkylating antineoplastic agent. purity: 99%
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